Sphingosine-1-Phosphate Signaling Regulates Myogenic Responsiveness in Human Resistance Arteries

• Sonya Hui ,

  Contributed equally to this work with: Sonya Hui, Andrew S. Levy

  Affiliations Toronto Centre for Microvascular Medicine, University of Toronto and St. Michael’s Hospital, Toronto, Canada, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Physiology, University of Toronto, Toronto, Canada

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• Andrew S. Levy ,

  Contributed equally to this work with: Sonya Hui, Andrew S. Levy

  Affiliations Toronto Centre for Microvascular Medicine, University of Toronto and St. Michael’s Hospital, Toronto, Canada, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Physiology, University of Toronto, Toronto, Canada

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• Daniel L. Slack,

  Affiliation Department of Physiology, University of Toronto, Toronto, Canada

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• Marcus J. Burnstein,

  Affiliations Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Surgery, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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• Lee Errett,

  Affiliations Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Surgery, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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• Daniel Bonneau,

  Affiliations Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Surgery, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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• David Latter,

  Affiliations Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Surgery, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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• Ori D. Rotstein,

  Affiliations Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Surgery, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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• Steffen-Sebastian Bolz ,

  * E-mail: sts.bolz@utoronto.ca

  ¶‡ These authors are senior authors on this work. These authors also contributed equally to this work.

  Affiliations Toronto Centre for Microvascular Medicine, University of Toronto and St. Michael’s Hospital, Toronto, Canada, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Physiology, University of Toronto, Toronto, Canada, Heart & Stroke / Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, Toronto, Canada

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• Darcy Lidington ,

  ¶‡ These authors are senior authors on this work. These authors also contributed equally to this work.

  Affiliations Toronto Centre for Microvascular Medicine, University of Toronto and St. Michael’s Hospital, Toronto, Canada, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Physiology, University of Toronto, Toronto, Canada

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• Julia Voigtlaender-Bolz

  ¶‡ These authors are senior authors on this work. These authors also contributed equally to this work.

  Affiliations Toronto Centre for Microvascular Medicine, University of Toronto and St. Michael’s Hospital, Toronto, Canada, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada, Department of Physiology, University of Toronto, Toronto, Canada, Department of Anaesthesia, St. Michael’s Hospital and University of Toronto, Toronto, Canada

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