High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer

Evert van den Broek; Maurits J. J. Dijkstra; Oscar Krijgsman; Daoud Sie; Josien C. Haan; Joleen J. H. Traets; Mark A. van de Wiel; Iris D. Nagtegaal; Cornelis J. A. Punt; Beatriz Carvalho; Bauke Ylstra; Sanne Abeln; Gerrit A. Meijer; Remond J. A. Fijneman

doi:10.1371/journal.pone.0138141

Loading metrics

Open Access

Peer-reviewed

Research Article

High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer

Evert van den Broek,

Current Address: Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Maurits J. J. Dijkstra,

Affiliation Department of Computer Science, VU University, Amsterdam, The Netherlands
⨯
Oscar Krijgsman,

Current Address: Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Daoud Sie,

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Josien C. Haan,

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Joleen J. H. Traets,

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Mark A. van de Wiel,

Affiliations Department of Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, The Netherlands, Department of Mathematics, VU University, Amsterdam, The Netherlands
⨯
Iris D. Nagtegaal,

Affiliation Department of Pathology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
⨯
Cornelis J. A. Punt,

Affiliation Department of Medical Oncology, Academic Medical Center, Amsterdam, The Netherlands
⨯
Beatriz Carvalho,

Current Address: Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Bauke Ylstra,

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Sanne Abeln,

Affiliation Department of Computer Science, VU University, Amsterdam, The Netherlands
⨯
Gerrit A. Meijer,

Current Address: Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Remond J. A. Fijneman

* E-mail: R.Fijneman@nki.nl

Current Address: Netherlands Cancer Institute, Amsterdam, The Netherlands

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯

High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer

Evert van den Broek,
Maurits J. J. Dijkstra,
Oscar Krijgsman,
Daoud Sie,
Josien C. Haan,
Joleen J. H. Traets,
Mark A. van de Wiel,
Iris D. Nagtegaal,
Cornelis J. A. Punt,
Beatriz Carvalho

Published: September 16, 2015
https://doi.org/10.1371/journal.pone.0138141

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Tumor suppressor genes
Is the Subject Area "Tumor suppressor genes" applicable to this article?

Thanks for your feedback.
Point mutation
Is the Subject Area "Point mutation" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Human genomics
Is the Subject Area "Human genomics" applicable to this article?

Thanks for your feedback.
Prognosis
Is the Subject Area "Prognosis" applicable to this article?

Thanks for your feedback.
Genome analysis
Is the Subject Area "Genome analysis" applicable to this article?

Thanks for your feedback.