Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

Georgios Grammatikos; Nerea Ferreiròs; Oliver Waidmann; Dimitra Bon; Sirkka Schroeter; Alexander Koch; Eva Herrmann; Stefan Zeuzem; Bernd Kronenberger; Josef Pfeilschifter

doi:10.1371/journal.pone.0138130

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Open Access

Peer-reviewed

Research Article

Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

Georgios Grammatikos ,

* E-mail: georgios.grammatikos@kgu.de

Affiliations Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany, Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany
⨯
Nerea Ferreiròs,

Affiliation Pharmazentrum Frankfurt, Institut für klinische Pharmakologie, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Oliver Waidmann,

Affiliation Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany
⨯
Dimitra Bon,

Affiliation Goethe University, Department of Medicine, Institute of Biostatistics and Mathematical Modelling, Frankfurt am Main, Germany
⨯
Sirkka Schroeter,

Affiliations Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany, Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany
⨯
Alexander Koch,

Affiliation Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany
⨯
Eva Herrmann,

Affiliation Goethe University, Department of Medicine, Institute of Biostatistics and Mathematical Modelling, Frankfurt am Main, Germany
⨯
Stefan Zeuzem,

Affiliation Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany
⨯
Bernd Kronenberger,

Affiliation Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany
⨯
Josef Pfeilschifter

Affiliation Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany
⨯

Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

Georgios Grammatikos,
Nerea Ferreiròs,
Oliver Waidmann,
Dimitra Bon,
Sirkka Schroeter,
Alexander Koch,
Eva Herrmann,
Stefan Zeuzem,
Bernd Kronenberger,
Josef Pfeilschifter

Published: September 18, 2015
https://doi.org/10.1371/journal.pone.0138130

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Cirrhosis
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Ascites
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Sphingolipids
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Hepatitis C virus
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Liver diseases
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