Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

• Daniela Herrera Moro Chao,

  Affiliations Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands, Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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• Wouter W. Kallemeijn,

  Affiliations Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands, Department of Biochemistry, Leiden Insitute of Chemistry, Leiden, The Netherlands

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• Andre R. A. Marques,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands

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• Marie Orre,

  Affiliation Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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• Roelof Ottenhoff,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands

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• Cindy van Roomen,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands

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• Ewout Foppen,

  Affiliation Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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• Maria C. Renner,

  Affiliation Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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• Martina Moeton,

  Affiliation Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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• Marco van Eijk,

  Affiliation Department of Biochemistry, Leiden Insitute of Chemistry, Leiden, The Netherlands

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• Rolf G. Boot,

  Affiliation Department of Biochemistry, Leiden Insitute of Chemistry, Leiden, The Netherlands

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• Willem Kamphuis,

  Affiliation Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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• Elly M. Hol,

  Affiliations Netherlands Institute for Neuroscience, Amsterdam, The Netherlands, Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands, Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands

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• Jan Aten,

  Affiliation Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands

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• Hermen S. Overkleeft,

  Affiliation Department of Bio-organic Synthesis, Leiden institute of Chemistry, Leiden, The Netherlands

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• Andries Kalsbeek,

  Affiliations Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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•  [ ... ],
• Johannes M. F. G. Aerts

  * E-mail: j.m.f.g.aerts@lic.leidenuniv.nl

  Affiliation Department of Biochemistry, Leiden Insitute of Chemistry, Leiden, The Netherlands

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