Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells

Daisuke Ishibashi; Takujiro Homma; Takehiro Nakagaki; Takayuki Fuse; Kazunori Sano; Hanae Takatsuki; Ryuichiro Atarashi; Noriyuki Nishida

doi:10.1371/journal.pone.0137958

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Open Access

Peer-reviewed

Research Article

Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells

Daisuke Ishibashi ,

* E-mail: dishi@nagasaki-u.ac.jp

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Takujiro Homma,

Current address: Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, Yamagata, Japan

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Takehiro Nakagaki,

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Takayuki Fuse,

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Kazunori Sano,

Current address: Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Hanae Takatsuki,

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Ryuichiro Atarashi,

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Noriyuki Nishida

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯

Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells

Daisuke Ishibashi,
Takujiro Homma,
Takehiro Nakagaki,
Takayuki Fuse,
Kazunori Sano,
Hanae Takatsuki,
Ryuichiro Atarashi,
Noriyuki Nishida

Published: September 14, 2015
https://doi.org/10.1371/journal.pone.0137958

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Animal prion diseases
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Prion diseases
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