Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

Thomas J. Cunningham; Thomas Brade; Lisa L. Sandell; Mark Lewandoski; Paul A. Trainor; Alexandre Colas; Mark Mercola; Gregg Duester

doi:10.1371/journal.pone.0137894

Loading metrics

Open Access

Peer-reviewed

Research Article

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

Thomas J. Cunningham,

Affiliation Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America
⨯
Thomas Brade,

Current Address: Department for Molecular Cardiology, Klinikum rechts der Isar Technical University Munich, Munich, Germany

Affiliation Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America
⨯
Lisa L. Sandell,

Affiliation Department of Molecular, Cellular, and Craniofacial Biology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Mark Lewandoski,

Affiliation Laboratory of Cancer and Developmental Biology, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
⨯
Paul A. Trainor,

Affiliations Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Alexandre Colas,

Affiliations Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America, Department of Bioengineering, University of California at San Diego, La Jolla, California, United States of America
⨯
Mark Mercola,

Affiliations Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America, Department of Bioengineering, University of California at San Diego, La Jolla, California, United States of America
⨯
Gregg Duester

* E-mail: duester@SBPdiscovery.org

Affiliation Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America
⨯

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

Thomas J. Cunningham,
Thomas Brade,
Lisa L. Sandell,
Mark Lewandoski,
Paul A. Trainor,
Alexandre Colas,
Mark Mercola,
Gregg Duester

Published: September 14, 2015
https://doi.org/10.1371/journal.pone.0137894

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Somites
Is the Subject Area "Somites" applicable to this article?

Thanks for your feedback.
Mesoderm
Is the Subject Area "Mesoderm" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Neural stem cell neurogenesis
Is the Subject Area "Neural stem cell neurogenesis" applicable to this article?

Thanks for your feedback.
Stem cell therapy
Is the Subject Area "Stem cell therapy" applicable to this article?

Thanks for your feedback.
Stem cells
Is the Subject Area "Stem cells" applicable to this article?

Thanks for your feedback.
Stem cell niche
Is the Subject Area "Stem cell niche" applicable to this article?

Thanks for your feedback.
Fibroblast growth factor
Is the Subject Area "Fibroblast growth factor" applicable to this article?

Thanks for your feedback.