A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Shunichi Odahara; Kan Uchiyama; Takahiro Kubota; Zensho Ito; Shinichiro Takami; Hiroko Kobayashi; Keisuke Saito; Shigeo Koido; Toshifumi Ohkusa

doi:10.1371/journal.pone.0137798

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Peer-reviewed

Research Article

A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Shunichi Odahara,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Kan Uchiyama ,

* E-mail: uchikan@jikei.ac.jp

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Takahiro Kubota,

Affiliation Department of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
⨯
Zensho Ito,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Shinichiro Takami,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Hiroko Kobayashi,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Keisuke Saito,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Shigeo Koido,

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯
Toshifumi Ohkusa

Affiliation Department of Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine (Kashiwa Hospital), Chiba, Japan
⨯

A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Shunichi Odahara,
Kan Uchiyama,
Takahiro Kubota,
Zensho Ito,
Shinichiro Takami,
Hiroko Kobayashi,
Keisuke Saito,
Shigeo Koido,
Toshifumi Ohkusa

Published: September 11, 2015
https://doi.org/10.1371/journal.pone.0137798

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