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Open Access

Peer-reviewed

Research Article

HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE^-/- Mice: Evidence of ABCA1 Down-Regulation

Claudine Tardy,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Marine Goffinet,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Nadia Boubekeur,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Guy Cholez,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Rose Ackermann,

Affiliation Cerenis Therapeutics Inc., Ann Arbor, Michigan, United States of America
⨯
Gavin Sy,

Affiliation Cerenis Therapeutics Inc., Ann Arbor, Michigan, United States of America
⨯
Constance Keyserling,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Narendra Lalwani,

Affiliation Cerenis Therapeutics Inc., Ann Arbor, Michigan, United States of America
⨯
John F. Paolini,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Jean-Louis Dasseux,

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Ronald Barbaras ,

* E-mail: barbaras@cerenis.com

Affiliation Cerenis Therapeutics SA, Labege, France
⨯
Rudi Baron

Affiliation Cerenis Therapeutics SA, Labege, France
⨯

HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE^-/- Mice: Evidence of ABCA1 Down-Regulation

Claudine Tardy,
Marine Goffinet,
Nadia Boubekeur,
Guy Cholez,
Rose Ackermann,
Gavin Sy,
Constance Keyserling,
Narendra Lalwani,
John F. Paolini,
Jean-Louis Dasseux

x

Published: September 3, 2015
https://doi.org/10.1371/journal.pone.0137584

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Cholesterol
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Macrophages
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Atherosclerosis
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Lipids
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Lipoproteins
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Carotid arteries
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Protein expression
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Phospholipids
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