RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes

Aline Jatho; Svenja Hartmann; Naim Kittana; Felicitas Mügge; Christina M. Wuertz; Malte Tiburcy; Wolfram-Hubertus Zimmermann; Dörthe M. Katschinski; Susanne Lutz

doi:10.1371/journal.pone.0137519

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Open Access

Peer-reviewed

Research Article

RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes

Aline Jatho,

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, Department of Cardiovascular Physiology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯
Svenja Hartmann,

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany, Division of Cell and Molecular Biophysics, King´s College London, London, United Kingdom
⨯
Naim Kittana,

Affiliation Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany
⨯
Felicitas Mügge,

Affiliation Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany
⨯
Christina M. Wuertz,

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯
Malte Tiburcy,

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯
Wolfram-Hubertus Zimmermann,

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯
Dörthe M. Katschinski,

Affiliations Department of Cardiovascular Physiology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯
Susanne Lutz

* E-mail: Susanne.Lutz@med.uni-goettingen.de

Affiliations Institute of Pharmacology, University Medical Center Göttingen, Georg-August-University, Germany, DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany
⨯

RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes

Aline Jatho,
Svenja Hartmann,
Naim Kittana,
Felicitas Mügge,
Christina M. Wuertz,
Malte Tiburcy,
Wolfram-Hubertus Zimmermann,
Dörthe M. Katschinski,
Susanne Lutz

Published: October 8, 2015
https://doi.org/10.1371/journal.pone.0137519

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