The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice

Xiao-Xia Hu; Li Fu; Yan Li; Ze-Bang Lin; Xiang Liu; Jing-Feng Wang; Yang-Xin Chen; Zhi-Ping Wang; Xi Zhang; Zhi-Jun Ou; Jing-Song Ou

doi:10.1371/journal.pone.0137405

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Research Article

The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice

Xiao-Xia Hu ,

Contributed equally to this work with: Xiao-Xia Hu, Li Fu

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Li Fu ,

Contributed equally to this work with: Xiao-Xia Hu, Li Fu

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Yan Li,

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Ze-Bang Lin,

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Xiang Liu,

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Jing-Feng Wang,

Affiliations Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, P.R. China, Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, P.R. China
⨯
Yang-Xin Chen,

Affiliations Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, P.R. China, Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, P.R. China
⨯
Zhi-Ping Wang,

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Xi Zhang,

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Zhi-Jun Ou ,

* E-mail: oujs@mail.sysu.edu.cn (J-SO); Zhijunou@163.com (Z-JO)

Affiliations The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Division of Hypertension and Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯
Jing-Song Ou

* E-mail: oujs@mail.sysu.edu.cn (J-SO); Zhijunou@163.com (Z-JO)

Affiliations Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, The Key Laboratory of Assisted Circulation, Ministry of Health, The First sAffiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China, Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, P.R. China
⨯

The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice

Xiao-Xia Hu,
Li Fu,
Yan Li,
Ze-Bang Lin,
Xiang Liu,
Jing-Feng Wang,
Yang-Xin Chen,
Zhi-Ping Wang,
Xi Zhang,
Zhi-Jun Ou

Published: September 2, 2015
https://doi.org/10.1371/journal.pone.0137405

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