Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity

Jonathan R. Brestoff; Tim Brodsky; Alexandra Z. Sosinsky; Ryan McLoughlin; Elena Stansky; Leila Fussell; Aaron Sheppard; Maria DiSanto-Rose; Erin E. Kershaw; Thomas H. Reynolds IV

doi:10.1371/journal.pone.0137388

Loading metrics

Open Access

Peer-reviewed

Research Article

Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity

Jonathan R. Brestoff,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Tim Brodsky,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Alexandra Z. Sosinsky,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Ryan McLoughlin,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Elena Stansky,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Leila Fussell,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Aaron Sheppard,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Maria DiSanto-Rose,

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯
Erin E. Kershaw,

Affiliation Division of Endocrinology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Thomas H. Reynolds IV

* E-mail: treynold@skidmore.edu

Affiliation Department of Health and Exercise Sciences, Skidmore College, Saratoga Springs, New York, United States of America
⨯

Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity

Jonathan R. Brestoff,
Tim Brodsky,
Alexandra Z. Sosinsky,
Ryan McLoughlin,
Elena Stansky,
Leila Fussell,
Aaron Sheppard,
Maria DiSanto-Rose,
Erin E. Kershaw,
Thomas H. Reynolds IV

Published: September 23, 2015
https://doi.org/10.1371/journal.pone.0137388

Reader Comments (3)

Post a new comment on this article

0 Responses

17 Jan 2016
15:16 GMT
Most Recent

Response to MnTBAP is neither SOD nor CATALASE mimic Posted by treynold on 17 Jan 2016 at 15:16 GMT
0 Responses

15 Jan 2016
18:49 GMT
Most Recent

MnTBAP promotes weight loss and reduces oxidative stress, but might not be an SOD or catalase mimic Posted by treynold on 15 Jan 2016 at 18:49 GMT
0 Responses

23 Dec 2015
22:59 GMT
Most Recent

MnTBAP is neither SOD nor CATALASE mimic Posted by ibatinic on 23 Dec 2015 at 22:59 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.
Adipose tissue
Is the Subject Area "Adipose tissue" applicable to this article?

Thanks for your feedback.
Obesity
Is the Subject Area "Obesity" applicable to this article?

Thanks for your feedback.
Body weight
Is the Subject Area "Body weight" applicable to this article?

Thanks for your feedback.
Insulin resistance
Is the Subject Area "Insulin resistance" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
Bioenergetics
Is the Subject Area "Bioenergetics" applicable to this article?

Thanks for your feedback.
Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.