Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

Jie Liu; Lijuan Wang; Feifei Zhao; Serena Tseng; Cyndhavi Narayanan; Lei Shura; Stephen Willingham; Maureen Howard; Susan Prohaska; Jens Volkmer; Mark Chao; Irving L. Weissman; Ravindra Majeti

doi:10.1371/journal.pone.0137345

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Open Access

Peer-reviewed

Research Article

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

Jie Liu,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Lijuan Wang,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Feifei Zhao,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Serena Tseng,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Cyndhavi Narayanan,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Lei Shura,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Stephen Willingham,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Maureen Howard,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Susan Prohaska,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Jens Volkmer,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Mark Chao,

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Irving L. Weissman ,

* E-mail: irv@stanford.edu (ILW); rmajeti@stanford.edu (RM)

Affiliation Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Ravindra Majeti

* E-mail: irv@stanford.edu (ILW); rmajeti@stanford.edu (RM)

Affiliations Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America, Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, United States of America
⨯

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

Jie Liu,
Lijuan Wang,
Feifei Zhao,
Serena Tseng,
Cyndhavi Narayanan,
Lei Shura,
Stephen Willingham,
Maureen Howard,
Susan Prohaska,
Jens Volkmer

Published: September 21, 2015
https://doi.org/10.1371/journal.pone.0137345

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