The Replacement of 10 Non-Conserved Residues in the Core Protein of JFH-1 Hepatitis C Virus Improves Its Assembly and Secretion

Loïc Etienne; Emmanuelle Blanchard; Audrey Boyer; Virginie Desvignes; Julien Gaillard; Jean-Christophe Meunier; Philippe Roingeard; Christophe Hourioux

doi:10.1371/journal.pone.0137182

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Peer-reviewed

Research Article

The Replacement of 10 Non-Conserved Residues in the Core Protein of JFH-1 Hepatitis C Virus Improves Its Assembly and Secretion

Loïc Etienne,

Current Address: Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.

Affiliation Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Emmanuelle Blanchard,

Affiliations Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France, Plate-forme des Microscopies, PPF ASB, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Audrey Boyer,

Affiliation Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Virginie Desvignes,

Affiliation Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Julien Gaillard,

Affiliation Plate-forme des Microscopies, PPF ASB, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Jean-Christophe Meunier,

Affiliation Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Philippe Roingeard,

Affiliations Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France, Plate-forme des Microscopies, PPF ASB, Université François Rabelais and CHRU de Tours, Tours, France
⨯
Christophe Hourioux

* E-mail: hourioux@med.univ-tours.fr

Affiliations Inserm U966, Faculté de medicine, Université François Rabelais and CHRU de Tours, Tours, France, Plate-forme des Microscopies, PPF ASB, Université François Rabelais and CHRU de Tours, Tours, France
⨯

The Replacement of 10 Non-Conserved Residues in the Core Protein of JFH-1 Hepatitis C Virus Improves Its Assembly and Secretion

Loïc Etienne,
Emmanuelle Blanchard,
Audrey Boyer,
Virginie Desvignes,
Julien Gaillard,
Jean-Christophe Meunier,
Philippe Roingeard,
Christophe Hourioux

Published: September 4, 2015
https://doi.org/10.1371/journal.pone.0137182

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Hepatitis C virus
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Protein structure
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