Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

• A. Francina Webster,

  Affiliations Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Canada

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• Nikolai Chepelev,

  Affiliation Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada

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• Rémi Gagné,

  Affiliation Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada

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• Byron Kuo,

  Affiliation Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada

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• Leslie Recio,

  Affiliation Integrated Laboratory Systems Inc., Research Triangle Park, North Carolina, United States of America

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• Andrew Williams,

  Affiliation Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada

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• Carole L. Yauk

  * E-mail: Carole.Yauk@hc-sc.gc.ca

  Current address: Environmental Health Science and Research Bureau, Health Canada, Tunney's Pasture, 50 Columbine Driveway, Ottawa, Ontario, Canada

  Affiliation Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada

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