The Role of End-of-Life Issues in the Design and Reporting of Cancer Clinical Trials: A Structured Literature Review

Jan Gaertner; Vera Weingärtner; Stefan Lange; Elke Hausner; Ansgar Gerhardus; Steffen T. Simon; Raymond Voltz; Gerhild Becker; Norbert Schmacke

doi:10.1371/journal.pone.0136640

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Open Access

Peer-reviewed

Research Article

The Role of End-of-Life Issues in the Design and Reporting of Cancer Clinical Trials: A Structured Literature Review

Jan Gaertner ,

Contributed equally to this work with: Jan Gaertner, Vera Weingärtner

* E-mail: jan.gaertner@uniklinik-freiburg.de

Affiliations Department of Palliative Care, University Medical Center Freiburg, Freiburg, Germany, Palliative Care Center of Excellence for Baden-Württemberg, Baden-Württemberg, Germany
⨯
Vera Weingärtner ,

Contributed equally to this work with: Jan Gaertner, Vera Weingärtner

Current address: Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany

Affiliation Department of Palliative Medicine, University Hospital of Cologne, Cologne, Germany
⨯
Stefan Lange,

Affiliation Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany
⨯
Elke Hausner,

Affiliation Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany
⨯
Ansgar Gerhardus,

Affiliations Institute for Public Health and Nursing Research (IPP), University of Bremen, Bremen, Germany, Health Sciences Bremen, University of Bremen, Bremen, Germany
⨯
Steffen T. Simon,

Affiliations Department of Palliative Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne/Bonn, Cologne/Bonn, Germany, Clinical Trials Unit (BMBF 01KN1106), University Hospital of Cologne, Cologne, Germany
⨯
Raymond Voltz,

Affiliations Department of Palliative Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne/Bonn, Cologne/Bonn, Germany, Clinical Trials Unit (BMBF 01KN1106), University Hospital of Cologne, Cologne, Germany
⨯
Gerhild Becker,

Affiliations Department of Palliative Care, University Medical Center Freiburg, Freiburg, Germany, Palliative Care Center of Excellence for Baden-Württemberg, Baden-Württemberg, Germany
⨯
Norbert Schmacke

Affiliations Institute for Public Health and Nursing Research (IPP), University of Bremen, Bremen, Germany, Health Sciences Bremen, University of Bremen, Bremen, Germany
⨯

The Role of End-of-Life Issues in the Design and Reporting of Cancer Clinical Trials: A Structured Literature Review

Jan Gaertner,
Vera Weingärtner,
Stefan Lange,
Elke Hausner,
Ansgar Gerhardus,
Steffen T. Simon,
Raymond Voltz,
Gerhild Becker,
Norbert Schmacke

Published: September 1, 2015
https://doi.org/10.1371/journal.pone.0136640

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