DNA-Launched Alphavirus Replicons Encoding a Fusion of Mycobacterial Antigens Acr and Ag85B Are Immunogenic and Protective in a Murine Model of TB Infection

Open Access

Peer-reviewed

Research Article

Neha Dalmia,

Affiliation Department of Microbiology, Immunology and Parasitology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America
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William B. Klimstra,

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Carol Mason,

Affiliation Department of Microbiology, Immunology and Parasitology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America
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Alistair J. Ramsay

* E-mail: aramsa@lsuhsc.edu

Affiliations Department of Microbiology, Immunology and Parasitology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America, Department of Microbiology, Immunology and Parasitology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America
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T cells
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Mycobacterium tuberculosis
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Antigens
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Immune response
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Cytotoxic T cells
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Mouse models
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Tuberculosis
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Animal models of infection
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