Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact

• Puya G. Yazdi ,

  Contributed equally to this work with: Puya G. Yazdi, Brian A. Pedersen

  Current Address: Systomic Health LLC, Los Angeles, California, United States of America

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America

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• Brian A. Pedersen ,

  Contributed equally to this work with: Puya G. Yazdi, Brian A. Pedersen

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America

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• Jared F. Taylor,

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America

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• Omar S. Khattab,

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America

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• Yu-Han Chen,

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America

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• Yumay Chen,

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America

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• Steven E. Jacobsen,

  Affiliations Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, California, United States of America, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California at Los Angeles, Los Angeles, California, United States of America, Howard Hughes Medical Institute, University of California at Los Angeles, Los Angeles, California, United States of America

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• Ping H. Wang

  * E-mail: phwang@uci.edu

  Affiliations UC Irvine Diabetes Center, University of California at Irvine, Irvine, California, United States of America, Sue and Bill Gross Stem Cell Research Center, University of California at Irvine, Irvine, California, United States of America, Department of Medicine, University of California at Irvine, Irvine, California, United States of America, Department of Biological Chemistry, University of California at Irvine, Irvine, California, United States of America, Department of Physiology & Biophysics, University of California at Irvine, Irvine, California, United States of America

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