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Open Access
Peer-reviewed
Research Article
Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion
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Zhen Gong,
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
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Jose M. Martin-Garcia,
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
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Sasha M. Daskalova,
Current Address: Center for BioEnergetics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287–5401, United States of America
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Felicia M. Craciunescu,
Affiliations Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center of Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287–5901, United States of America
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Lusheng Song,
Affiliation Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–6401, United States of America
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Katerina Dörner,
Current Address: Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
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Debra T. Hansen,
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center of Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287–5901, United States of America
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Jay-How Yang,
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
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Joshua LaBaer,
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–6401, United States of America
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Brenda G. Hogue,
Affiliations Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287–5401, United States of America, School of Life Sciences, Arizona State University, Tempe, AZ 85287–4501, United States of America
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Tsafrir S. Mor ,
* E-mail: tsafrir.mor@asu.edu (TSM); pfromme@asu.edu (PF)
Affiliations Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287–5401, United States of America, School of Life Sciences, Arizona State University, Tempe, AZ 85287–4501, United States of America
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Petra Fromme
* E-mail: tsafrir.mor@asu.edu (TSM); pfromme@asu.edu (PF)
Affiliations Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287–1604, United States of America, Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287–1604, United States of America
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Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion
- Zhen Gong,
- Jose M. Martin-Garcia,
- Sasha M. Daskalova,
- Felicia M. Craciunescu,
- Lusheng Song,
- Katerina Dörner,
- Debra T. Hansen,
- Jay-How Yang,
- Joshua LaBaer,
- Brenda G. Hogue
- Published: August 21, 2015
- https://doi.org/10.1371/journal.pone.0136507