Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

Clément Guillou; Céline Derambure; Manuel Fréret; Mathieu Verdet; Gilles Avenel; Marie-Laure Golinski; Jean-Christophe Sabourin; François Le Loarer; Sahil Adriouch; Olivier Boyer; Thierry Lequerré; Olivier Vittecoq

doi:10.1371/journal.pone.0136359

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Open Access

Peer-reviewed

Research Article

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

Clément Guillou,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France
⨯
Céline Derambure,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France
⨯
Manuel Fréret,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France
⨯
Mathieu Verdet,

Affiliation Rouen University Hospital, Department of Rheumatology, Rouen, France
⨯
Gilles Avenel,

Affiliation Rouen University Hospital, Department of Rheumatology, Rouen, France
⨯
Marie-Laure Golinski,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France
⨯
Jean-Christophe Sabourin,

Affiliations Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, Rouen University Hospital, Department of Pathology, Rouen, France
⨯
François Le Loarer,

Affiliation Rouen University Hospital, Department of Pathology, Rouen, France
⨯
Sahil Adriouch,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France
⨯
Olivier Boyer,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, Rouen University Hospital, Department of Immunology, Rouen, France
⨯
Thierry Lequerré,

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, Rouen University Hospital, Department of Rheumatology, Rouen, France
⨯
Olivier Vittecoq

* E-mail: olivier.vittecoq@chu-rouen.fr

Affiliations INSERM, U905, Rouen, France, Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, Rouen University Hospital, Department of Rheumatology, Rouen, France
⨯

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

Clément Guillou,
Céline Derambure,
Manuel Fréret,
Mathieu Verdet,
Gilles Avenel,
Marie-Laure Golinski,
Jean-Christophe Sabourin,
François Le Loarer,
Sahil Adriouch,
Olivier Boyer

Published: August 24, 2015
https://doi.org/10.1371/journal.pone.0136359

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Antibodies
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Arthritis
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Enzyme-linked immunoassays
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