Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions

• Alessandra Silvestri ,

  * E-mail: silvestri.alessandra@gmail.com

  Current address: cpo - cellular phenomics & oncology GmbH, Berlin, Germany

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Francesco Palumbo,

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Ignazio Rasi,

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Daniela Posca,

  Current address: Department of Experimental Oncology, Regina Elena National Cancer Institute, Rome, Italy

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Theodora Pavlidou,

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Serena Paoluzi,

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Luisa Castagnoli,

  Affiliation Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy

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• Giovanni Cesareni

  Affiliations Laboratory of Molecular Genetics, Department of Biology, Tor Vergata University, Rome, Italy, IRCCS, Fondazione Santa Lucia, Rome, Italy

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