Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase

Open Access

Peer-reviewed

Research Article

Amol Bhargava,

Affiliations Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada, Inflammation Research Network, University of Calgary, Calgary, Alberta, Canada, Host-Parasite Interactions, University of Calgary, Calgary, Alberta, Canada
⨯
James A. Cotton,

Affiliations Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada, Inflammation Research Network, University of Calgary, Calgary, Alberta, Canada, Host-Parasite Interactions, University of Calgary, Calgary, Alberta, Canada
⨯
Brent R. Dixon,

Affiliation Bureau of Microbial Hazards, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada
⨯
Lashitew Gedamu,

Affiliations Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada, Host-Parasite Interactions, University of Calgary, Calgary, Alberta, Canada
⨯
Robin M. Yates,

Affiliations Department of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Alberta, Canada, Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada
⨯
Andre G. Buret

* E-mail: aburet@ucalgary.ca

Affiliations Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada, Inflammation Research Network, University of Calgary, Calgary, Alberta, Canada, Host-Parasite Interactions, University of Calgary, Calgary, Alberta, Canada
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Trophozoites
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Cysteine proteases
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Gastrointestinal tract
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Giardia
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Parasitic intestinal diseases
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Cytoskeletal proteins
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Intestinal parasites
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Proteases
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