Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

Elise Rousseau; Michael Joubert; Géraldine Trzepla; Jean Jacques Parienti; Thomas Freret; Marie Christine Vanthygem; Rachel Desailloud; Hervé Lefebvre; Antoine Coquerel; Yves Reznik; PHAD Study Group

doi:10.1371/journal.pone.0135975

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Open Access

Peer-reviewed

Research Article

Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

Elise Rousseau ,

Contributed equally to this work with: Elise Rousseau, Michael Joubert

Affiliation Department of Endocrinology, Caen University Hospital, 14033, Caen, France
⨯
Michael Joubert ,

Contributed equally to this work with: Elise Rousseau, Michael Joubert

Affiliation Department of Endocrinology, Caen University Hospital, 14033, Caen, France
⨯
Géraldine Trzepla,

Affiliation Department of Endocrinology, Caen University Hospital, 14033, Caen, France
⨯
Jean Jacques Parienti,

Affiliations Department of Clinical Research, Caen University Hospital, 14033, Caen, France, University of Caen Basse-Normandie, Medical School, Caen, F-14032, France
⨯
Thomas Freret,

Affiliations UFR Pharmaceutical Sciences, EA4259, University of Caen Basse-Normandie, 14032, Caen, France, University of Caen Basse-Normandie, Medical School, Caen, F-14032, France
⨯
Marie Christine Vanthygem,

Affiliation Department of Endocrinology, Lille University Hospital, 59037, Lille, France
⨯
Rachel Desailloud,

Affiliation Department of Endocrinology, Amiens University Hospital, Hopital SUD, 80054, Amiens, France
⨯
Hervé Lefebvre,

Affiliation Department of Endocrinology and INSERM U413, IFRMP23, Rouen University Hospital, 76031, Rouen, France
⨯
Antoine Coquerel,

Affiliations Department of Pharmacology, Caen University Hospital, 14033, Caen, France, University of Caen Basse-Normandie, Medical School, Caen, F-14032, France
⨯
Yves Reznik ,

* E-mail: reznik-y@chu-caen.fr

Affiliations Department of Endocrinology, Caen University Hospital, 14033, Caen, France, University of Caen Basse-Normandie, Medical School, Caen, F-14032, France
⨯
PHAD Study Group

¶Membership of the PHAD Study Group is listed in the Acknowledgments.
⨯

Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

Elise Rousseau,
Michael Joubert,
Géraldine Trzepla,
Jean Jacques Parienti,
Thomas Freret,
Marie Christine Vanthygem,
Rachel Desailloud,
Hervé Lefebvre,
Antoine Coquerel,
Yves Reznik

Published: August 28, 2015
https://doi.org/10.1371/journal.pone.0135975

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