Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago

Desarae Echevarria; Alexander Gutfraind; Basmattee Boodram; Marian Major; Sara Del Valle; Scott J Cotler; Harel Dahari

doi:10.1371/journal.pone.0135901

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Peer-reviewed

Research Article

Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago

Desarae Echevarria,

Affiliation The Program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Chicago, Medical Center, Maywood, Illinois, United States of America
⨯
Alexander Gutfraind,

Affiliations The Program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Chicago, Medical Center, Maywood, Illinois, United States of America, Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Basmattee Boodram,

Affiliation Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Marian Major,

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America
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Sara Del Valle,

Affiliation Energy and Infrastructure Analysis Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Scott J Cotler,

Affiliation The Program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Chicago, Medical Center, Maywood, Illinois, United States of America
⨯
Harel Dahari

* E-mail: hdahari@lumc.edu

Affiliations The Program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Chicago, Medical Center, Maywood, Illinois, United States of America, Theoretical and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
⨯

Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago

Desarae Echevarria,
Alexander Gutfraind,
Basmattee Boodram,
Marian Major,
Sara Del Valle,
Scott J Cotler,
Harel Dahari

Published: August 21, 2015
https://doi.org/10.1371/journal.pone.0135901

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Immunity
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Hepatitis C virus
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Antiviral immune response
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RNA analysis
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