Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

• André R. A. Marques ,

  Contributed equally to this work with: André R. A. Marques, Jan Aten

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Jan Aten ,

  Contributed equally to this work with: André R. A. Marques, Jan Aten

  Affiliation Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Roelof Ottenhoff,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Cindy P. A. A. van Roomen,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Daniela Herrera Moro,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Nike Claessen,

  Affiliation Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• María Fernanda Vinueza Veloz,

  Affiliation Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands

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• Kuikui Zhou,

  Affiliation Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands

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• Zhanmin Lin,

  Affiliation Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands

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• Mina Mirzaian,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Rolf G. Boot,

  Affiliation Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands

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• Chris I. De Zeeuw,

  Affiliations Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands, Netherlands Institute for Neuroscience, Royal Dutch Academy of Arts & Sciences, 1105 BA, Amsterdam, The Netherlands

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• Herman S. Overkleeft,

  Affiliation Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands

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• Yildiz Yildiz,

  Affiliation Department of Internal Medicine, Hospital of Bregenz, 6900, Bregenz, Austria

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• Johannes M. F. G. Aerts

  * E-mail: j.m.f.g.aerts@lic.leidenuniv.nl

  Affiliations Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands, Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands

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