Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes

Laura Tarnawski; Xiaojie Xian; Gustavo Monnerat; Iain C. Macaulay; Daniela Malan; Andrew Borgman; Sean M. Wu; Bernd K. Fleischmann; Stefan Jovinge

doi:10.1371/journal.pone.0135880

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Open Access

Peer-reviewed

Research Article

Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes

Laura Tarnawski ,

* E-mail: laura.tarnawski@vai.org

Current address: Van Andel Research Institute, Grand Rapids, Michigan, United States of America

Affiliation Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden
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Xiaojie Xian,

Affiliation Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden
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Gustavo Monnerat,

Affiliations Institute of Physiology I, Life and Brain Center, Department of Cardiac Surgery, University of Bonn, Bonn, Germany, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
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Iain C. Macaulay,

Affiliation Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, England
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Daniela Malan,

Affiliation Institute of Physiology I, Life and Brain Center, Department of Cardiac Surgery, University of Bonn, Bonn, Germany
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Andrew Borgman,

Affiliation Spectrum Health Fredrik Meijer Heart and Vascular Institute, Grand Rapids, Michigan, United States of America
⨯
Sean M. Wu,

Affiliations Institute for Stem Cell Biology and Regenerative Medicine, Stanford, California, United States of America, Stanford Cardiovascular Institute, Stanford, California, United States of America, Dept of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, California, United States of America
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Bernd K. Fleischmann,

Affiliations Institute of Physiology I, Life and Brain Center, Department of Cardiac Surgery, University of Bonn, Bonn, Germany, Pharma Center Bonn, University of Bonn, Bonn, Germany
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Stefan Jovinge

Affiliations Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, Spectrum Health Fredrik Meijer Heart and Vascular Institute, Grand Rapids, Michigan, United States of America
⨯

Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes

Laura Tarnawski,
Xiaojie Xian,
Gustavo Monnerat,
Iain C. Macaulay,
Daniela Malan,
Andrew Borgman,
Sean M. Wu,
Bernd K. Fleischmann,
Stefan Jovinge

Published: August 31, 2015
https://doi.org/10.1371/journal.pone.0135880

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Cardiomyocytes
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Heart
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Integrins
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Gene expression
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Myocardium
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Polymerase chain reaction
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Cardiac ventricles
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Stem cell therapy
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