Dopaminergic Toxin 1-Methyl-4-Phenylpyridinium, Proteins α-Synuclein and Glia Maturation Factor Activate Mast Cells and Release Inflammatory Mediators

Duraisamy Kempuraj; Ramasamy Thangavel; Evert Yang; Sagar Pattani; Smita Zaheer; Donna A. Santillan; Mark K. Santillan; Asgar Zaheer

doi:10.1371/journal.pone.0135776

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Research Article

Dopaminergic Toxin 1-Methyl-4-Phenylpyridinium, Proteins α-Synuclein and Glia Maturation Factor Activate Mast Cells and Release Inflammatory Mediators

Duraisamy Kempuraj,

Affiliations Veterans Affairs Health Care System, Iowa City, Iowa, United States of America, Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Ramasamy Thangavel,

Affiliations Veterans Affairs Health Care System, Iowa City, Iowa, United States of America, Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Evert Yang,

Affiliation Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Sagar Pattani,

Affiliation Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Smita Zaheer,

Affiliation Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Donna A. Santillan,

Affiliation Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Mark K. Santillan,

Affiliation Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯
Asgar Zaheer

* E-mail: asgar-zaheer@uiowa.edu

Affiliations Veterans Affairs Health Care System, Iowa City, Iowa, United States of America, Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America
⨯

Dopaminergic Toxin 1-Methyl-4-Phenylpyridinium, Proteins α-Synuclein and Glia Maturation Factor Activate Mast Cells and Release Inflammatory Mediators

Duraisamy Kempuraj,
Ramasamy Thangavel,
Evert Yang,
Sagar Pattani,
Smita Zaheer,
Donna A. Santillan,
Mark K. Santillan,
Asgar Zaheer

Published: August 14, 2015
https://doi.org/10.1371/journal.pone.0135776

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