Osteopontin Deficiency Accelerates Spontaneous Colitis in Mice with Disrupted Gut Microbiota and Macrophage Phagocytic Activity

• Takahiko Toyonaga,

  Affiliation Department of Gastroenterology and Hepatology, Kansai Medical University, Hirakata, Osaka, Japan

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• Hiroshi Nakase ,

  * E-mail: hiropy_n@kuhp.kyoto-u.ac.jp

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Satoru Ueno,

  Affiliation Department of Internal medicine, Takashima Municipal Hospital, Takashima, Shiga, Japan

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• Minoru Matsuura,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Takuya Yoshino,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Yusuke Honzawa,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Ayako Itou,

  Affiliation Nutritional Science Institute, Morinaga Milk Industry Co., Ltd, Zama, Kanagawa, Japan

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• Kazuyoshi Namba,

  Affiliation Nutritional Science Institute, Morinaga Milk Industry Co., Ltd, Zama, Kanagawa, Japan

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• Naoki Minami,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Satoshi Yamada,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Yorimitsu Koshikawa,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Toshimitsu Uede,

  Affiliation Department of Matrix Medicine, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Tsutomu Chiba,

  Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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• Kazuichi Okazaki

  Affiliation Department of Gastroenterology and Hepatology, Kansai Medical University, Hirakata, Osaka, Japan

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