Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene

• Diego Bertoli,

  Affiliation CREA, Diagnostics Department, Spedali Civili of Brescia, Brescia, Italy

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• Federico Serana,

  Affiliation CREA, Diagnostics Department, Spedali Civili of Brescia, Brescia, Italy

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• Alessandra Sottini,

  Affiliation CREA, Diagnostics Department, Spedali Civili of Brescia, Brescia, Italy

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• Cinzia Cordioli,

  Affiliation Multiple Sclerosis Center, Spedali Civili of Brescia, Presidio di Montichiari, Brescia, Italy

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• Davide Maimone,

  Affiliation Department of Neurology, Garibaldi Hospital, Catania, Italy

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• Maria Pia Amato,

  Affiliation Department of Neurology, University of Florence–Careggi Hospital, Florence, Italy

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• Diego Centonze,

  Affiliation Department of Neurosciences Tor Vergata University, S. Lucia Foundation IRCCS, Rome, Italy

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• Ciro Florio,

  Affiliation Department of Neurology, Ospedale Caldarelli, Napoli, Italy

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• Elisa Puma,

  Affiliation Biogen Italy, Medical Department, Milan, Italy

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• Ruggero Capra,

  Affiliation Multiple Sclerosis Center, Spedali Civili of Brescia, Presidio di Montichiari, Brescia, Italy

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• Luisa Imberti

  * E-mail: limberti@yahoo.it

  Affiliation CREA, Diagnostics Department, Spedali Civili of Brescia, Brescia, Italy

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