Melatonin Cytotoxicity Is Associated to Warburg Effect Inhibition in Ewing Sarcoma Cells

Ana M. Sanchez-Sanchez; Isaac Antolin; Noelia Puente-Moncada; Santos Suarez; Marina Gomez-Lobo; Carmen Rodriguez; Vanesa Martin

doi:10.1371/journal.pone.0135420

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Peer-reviewed

Research Article

Melatonin Cytotoxicity Is Associated to Warburg Effect Inhibition in Ewing Sarcoma Cells

Ana M. Sanchez-Sanchez,

Affiliations Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯
Isaac Antolin,

Affiliations Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯
Noelia Puente-Moncada,

Affiliations Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯
Santos Suarez,

Affiliation Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain
⨯
Marina Gomez-Lobo,

Affiliation Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯
Carmen Rodriguez,

Affiliations Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯
Vanesa Martin

* E-mail: martinvanesa@uniovi.es

Affiliations Departamento de Morfología y Biología Celular, Facultad de Medicina, c/Julian Claveria, 33006 Oviedo, University of Oviedo, Oviedo, Spain, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Spain
⨯

Melatonin Cytotoxicity Is Associated to Warburg Effect Inhibition in Ewing Sarcoma Cells

Ana M. Sanchez-Sanchez,
Isaac Antolin,
Noelia Puente-Moncada,
Santos Suarez,
Marina Gomez-Lobo,
Carmen Rodriguez,
Vanesa Martin

Published: August 7, 2015
https://doi.org/10.1371/journal.pone.0135420

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Melatonin
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Ewing sarcoma
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Glycogens
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Glucose
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Glucose metabolism
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Warburg effect
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Cancers and neoplasms
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Cell metabolism
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