Molecular Cloning, Heterologous Expression, and Functional Characterization of an NADPH-Cytochrome P450 Reductase Gene from Camptotheca acuminata, a Camptothecin-Producing Plant

Xixing Qu; Xiang Pu; Fei Chen; Yun Yang; Lixia Yang; Guolin Zhang; Yinggang Luo

doi:10.1371/journal.pone.0135397

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Research Article

Molecular Cloning, Heterologous Expression, and Functional Characterization of an NADPH-Cytochrome P450 Reductase Gene from Camptotheca acuminata, a Camptothecin-Producing Plant

Xixing Qu ,

Contributed equally to this work with: Xixing Qu, Xiang Pu

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, University of Chinese Academy of Sciences, Beijing, PR China
⨯
Xiang Pu ,

Contributed equally to this work with: Xixing Qu, Xiang Pu

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, University of Chinese Academy of Sciences, Beijing, PR China
⨯
Fei Chen,

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, University of Chinese Academy of Sciences, Beijing, PR China
⨯
Yun Yang,

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, University of Chinese Academy of Sciences, Beijing, PR China
⨯
Lixia Yang,

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, University of Chinese Academy of Sciences, Beijing, PR China
⨯
Guolin Zhang,

Affiliation Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China
⨯
Yinggang Luo

* E-mail: yinggluo@cib.ac.cn

Affiliations Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China, State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, PR China
⨯

Molecular Cloning, Heterologous Expression, and Functional Characterization of an NADPH-Cytochrome P450 Reductase Gene from Camptotheca acuminata, a Camptothecin-Producing Plant

Xixing Qu,
Xiang Pu,
Fei Chen,
Yun Yang,
Lixia Yang,
Guolin Zhang,
Yinggang Luo

Published: August 7, 2015
https://doi.org/10.1371/journal.pone.0135397

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