Biochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A

Jui-Hsin Huang; Zhe-Qing Shen; Shu-Pei Lien; Kuang-Nan Hsiao; Chih-Hsiang Leng; Chi-Chang Chen; Leung-Kei Siu; Pele Choi-Sing Chong

doi:10.1371/journal.pone.0135045

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Open Access

Peer-reviewed

Research Article

Biochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A

Jui-Hsin Huang,

Affiliations Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan, Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan
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Zhe-Qing Shen,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
⨯
Shu-Pei Lien,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
⨯
Kuang-Nan Hsiao,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
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Chih-Hsiang Leng,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
⨯
Chi-Chang Chen,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
⨯
Leung-Kei Siu,

Affiliation Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
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Pele Choi-Sing Chong

* E-mail: pelechong@nhri.org.tw

Affiliations Vaccine R&D Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan, Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan, Graduate Institute of Immunology, China Medical University, Taichung, Taiwan
⨯

Biochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A

Jui-Hsin Huang,
Zhe-Qing Shen,
Shu-Pei Lien,
Kuang-Nan Hsiao,
Chih-Hsiang Leng,
Chi-Chang Chen,
Leung-Kei Siu,
Pele Choi-Sing Chong

Published: August 13, 2015
https://doi.org/10.1371/journal.pone.0135045

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