Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases

Bryan M. Zhao; Sarah L. Keasey; Joseph E. Tropea; George T. Lountos; Beverly K. Dyas; Scott Cherry; Sreejith Raran-Kurussi; David S. Waugh; Robert G. Ulrich

doi:10.1371/journal.pone.0134984

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Open Access

Peer-reviewed

Research Article

Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases

Bryan M. Zhao,

Affiliations Molecular and Translational Sciences Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, 21702, United States of America, The Geneva Foundation, Tacoma, WA, 98402, United States of America
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Sarah L. Keasey,

Affiliation Molecular and Translational Sciences Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, 21702, United States of America
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Joseph E. Tropea,

Affiliation Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America
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George T. Lountos,

Affiliations Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America, Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, 21702, United States of America
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Beverly K. Dyas,

Affiliation Molecular and Translational Sciences Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, 21702, United States of America
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Scott Cherry,

Affiliation Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America
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Sreejith Raran-Kurussi,

Affiliation Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America
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David S. Waugh,

Affiliation Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America
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Robert G. Ulrich

* E-mail: rulrich@bhsai.org

Affiliation Molecular and Translational Sciences Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, 21702, United States of America
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Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases

Bryan M. Zhao,
Sarah L. Keasey,
Joseph E. Tropea,
George T. Lountos,
Beverly K. Dyas,
Scott Cherry,
Sreejith Raran-Kurussi,
David S. Waugh,
Robert G. Ulrich

Published: August 24, 2015
https://doi.org/10.1371/journal.pone.0134984

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21 Sep 2015
20:54 GMT
Most Recent

DUSP (and CDC25) is not the same same fold Posted by mjchen on 16 Sep 2015 at 20:22 GMT

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Microarrays
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Phosphatases
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Sequence motif analysis
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Signal peptides
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Sequence alignment
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Phylogenetics
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Protein sequencing
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Tyrosine
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