Membrane-Active Sequences within gp41 Membrane Proximal External Region (MPER) Modulate MPER-Containing Peptidyl Fusion Inhibitor Activity and the Biosynthesis of HIV-1 Structural Proteins

Open Access

Peer-reviewed

Research Article

Si Min Zhang,

Affiliations Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, SE-141 86, Sweden, School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore
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Alenka Jejcic,

Affiliation Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Minderbroederstraat 10, Leuven, B-3000, Belgium
⨯
James P. Tam,

Affiliation School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore
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Anders Vahlne

* E-mail: anders.vahlne@ki.se

Affiliation Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, SE-141 86, Sweden
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HIV-1
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Membrane fusion
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Viral entry
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Cell membranes
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Virions
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Dimerization
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Lipids
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Membrane proteins
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