NMR and MD Studies Reveal That the Isolated Dengue NS3 Protease Is an Intrinsically Disordered Chymotrypsin Fold Which Absolutely Requests NS2B for Correct Folding and Functional Dynamics

Open Access

Peer-reviewed

Research Article

Garvita Gupta,

Affiliation Department of Biological Sciences, Faculty of Science, National University of Singapore, 10 Kent Ridge Crescent, Singapore, Singapore
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Liangzhong Lim,

Affiliation Department of Biological Sciences, Faculty of Science, National University of Singapore, 10 Kent Ridge Crescent, Singapore, Singapore
⨯
Jianxing Song

* E-mail: dbssjx@nus.edu.sg

Affiliation Department of Biological Sciences, Faculty of Science, National University of Singapore, 10 Kent Ridge Crescent, Singapore, Singapore
⨯

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Proteases
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Dengue fever
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Crystal structure
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Molecular dynamics
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Biochemical simulations
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Dengue virus
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Enzyme structure
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SARS
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