Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

Loris De Cecco; Matteo Capaia; Simona Zupo; Giovanna Cutrona; Serena Matis; Antonella Brizzolara; Anna Maria Orengo; Michela Croce; Edoardo Marchesi; Manlio Ferrarini; Silvana Canevari; Silvano Ferrini

doi:10.1371/journal.pone.0134706

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Peer-reviewed

Research Article

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

Loris De Cecco,

Affiliation Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Matteo Capaia,

Affiliation Laboratory of Biotherapy, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Simona Zupo,

Affiliation Laboratory of Molecular Diagnostics, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Giovanna Cutrona,

Affiliation Laboratory of Molecular Diagnostics, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Serena Matis,

Affiliation Scientific Direction, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Antonella Brizzolara,

Affiliation Laboratory of Biotherapy, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Anna Maria Orengo,

Affiliation Laboratory of Biotherapy, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Michela Croce,

Affiliation Laboratory of Biotherapy, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Edoardo Marchesi,

Affiliation Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Manlio Ferrarini,

Affiliation Scientific Direction, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯
Silvana Canevari ,

* E-mail: silvanodomenico.ferrini@hsanmartino.it (SF); silvana.canevari@istitutotumori.mi.it (SC)

Affiliation Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Silvano Ferrini

* E-mail: silvanodomenico.ferrini@hsanmartino.it (SF); silvana.canevari@istitutotumori.mi.it (SC)

Affiliation Laboratory of Biotherapy, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
⨯

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

Loris De Cecco,
Matteo Capaia,
Simona Zupo,
Giovanna Cutrona,
Serena Matis,
Antonella Brizzolara,
Anna Maria Orengo,
Michela Croce,
Edoardo Marchesi,
Manlio Ferrarini

Published: August 25, 2015
https://doi.org/10.1371/journal.pone.0134706

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