Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance

Peng Yu; Jing Zhang; Shuchun Yu; Zhenzhong Luo; Fuzhou Hua; Linhui Yuan; Zhidong Zhou; Qin Liu; Xiaohong Du; Sisi Chen; Lieliang Zhang; Guohai Xu

doi:10.1371/journal.pone.0134666

Loading metrics

Open Access

Peer-reviewed

Research Article

Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance

Peng Yu ,

Contributed equally to this work with: Peng Yu, Jing Zhang

Affiliation Department of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Jing Zhang ,

Contributed equally to this work with: Peng Yu, Jing Zhang

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Shuchun Yu,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Zhenzhong Luo,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Fuzhou Hua,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Linhui Yuan,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Zhidong Zhou,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Qin Liu,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Xiaohong Du,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Sisi Chen,

Affiliation Department of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Lieliang Zhang,

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯
Guohai Xu

* E-mail: xuguohai@sina.com

Affiliation Department of Anesthesiology, the Second Affiliated Hospital of Nanchang University, Nanchang 330000, China
⨯

Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance

Peng Yu,
Jing Zhang,
Shuchun Yu,
Zhenzhong Luo,
Fuzhou Hua,
Linhui Yuan,
Zhidong Zhou,
Qin Liu,
Xiaohong Du,
Sisi Chen

Published: August 11, 2015
https://doi.org/10.1371/journal.pone.0134666

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Autophagic cell death
Is the Subject Area "Autophagic cell death" applicable to this article?

Thanks for your feedback.
Reperfusion
Is the Subject Area "Reperfusion" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Oxidative stress
Is the Subject Area "Oxidative stress" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Myocardium
Is the Subject Area "Myocardium" applicable to this article?

Thanks for your feedback.
Immunoblotting
Is the Subject Area "Immunoblotting" applicable to this article?

Thanks for your feedback.