Kidney Dysfunction in Adult Offspring Exposed In Utero to Type 1 Diabetes Is Associated with Alterations in Genome-Wide DNA Methylation

• Jean-François Gautier ,

  * E-mail: jean-francois.gautier@lrb.aphp.fr

  Affiliations Department of Diabetes and Endocrinology, Assistance Publique—Hôpitaux de Paris, DHU FIRE, Lariboisière Hospital, University Paris-Diderot Paris-7, Paris, France, Clinical Investigation Center, INSERM-CIC9504, Saint-Louis University Hospital, Assistance Publique—Hôpitaux de Paris, University Paris-Diderot Paris-7, Paris, France, INSERM UMRS 1138, Cordeliers Research Center, University Pierre et Marie Curie Paris-6, Paris, France

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• Raphaël Porcher,

  Affiliation Department of Biostatistics and Medical Computing, Saint-Louis University Hospital, Assistance Publique—Hôpitaux de Paris, University Paris-Diderot Paris-7, Paris, France

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• Charbel Abi Khalil,

  Affiliation Department of Diabetes, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique—Hôpitaux de Paris, DHU FIRE, University Paris-Diderot Paris-7, Paris, France

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• Naima Bellili-Munoz,

  Affiliation INSERM UMRS 1138, Cordeliers Research Center, University Pierre et Marie Curie Paris-6, Paris, France

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• Lila Sabrina Fetita,

  Affiliation Department of Diabetes and Endocrinology, Assistance Publique—Hôpitaux de Paris, DHU FIRE, Lariboisière Hospital, University Paris-Diderot Paris-7, Paris, France

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• Florence Travert,

  Affiliations Department of Diabetes, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique—Hôpitaux de Paris, DHU FIRE, University Paris-Diderot Paris-7, Paris, France, Clinical Investigation Center, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique–Hôpitaux de Paris, University Paris-Diderot Paris-7, Paris, France

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• Simeon-Pierre Choukem,

  Affiliation Department of Diabetes and Endocrinology, Assistance Publique—Hôpitaux de Paris, DHU FIRE, Lariboisière Hospital, University Paris-Diderot Paris-7, Paris, France

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• Jean-Pierre Riveline,

  Affiliations INSERM UMRS 1138, Cordeliers Research Center, University Pierre et Marie Curie Paris-6, Paris, France, Department of Diabetes and Endocrinology, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France

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• Samy Hadjadj,

  Affiliation Department of Endocrinology and Diabetes, Centre Hospitalier Universitaire, Poitiers, France

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• Etienne Larger,

  Affiliation Department of Diabetes, Hôtel-Dieu Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France

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• Philippe Boudou,

  Affiliation Unit of Transfer in Molecular Oncology and Hormonology, Saint-Louis University Hospital, Assistance Publique—Hôpitaux de Paris, Paris, France

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• Bertrand Blondeau,

  Affiliation INSERM UMRS 1138, Cordeliers Research Center, University Pierre et Marie Curie Paris-6, Paris, France

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• Ronan Roussel,

  Affiliations Department of Diabetes, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique—Hôpitaux de Paris, DHU FIRE, University Paris-Diderot Paris-7, Paris, France, INSERM U695, University Paris-Diderot Paris-7, Paris, France

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• Pascal Ferré,

  Affiliation INSERM UMRS 1138, Cordeliers Research Center, University Pierre et Marie Curie Paris-6, Paris, France

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• Eric Ravussin,

  Affiliation Penington Biomedical Research Center, Baton Rouge, LA, United States of America

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• François Rouzet,

  Affiliation Department of Nuclear Medicine, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique—Hôpitaux de Paris, University Paris-Diderot Paris-7, Paris, France

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•  [ ... ],
• Michel Marre

  Affiliations Department of Diabetes, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique—Hôpitaux de Paris, DHU FIRE, University Paris-Diderot Paris-7, Paris, France, Clinical Investigation Center, Groupe Hospitalier Bichat—Claude Bernard, Assistance Publique–Hôpitaux de Paris, University Paris-Diderot Paris-7, Paris, France, INSERM U695, University Paris-Diderot Paris-7, Paris, France

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