Preclinical Evaluation of a Potential GSH Ester Based PET/SPECT Imaging Probe DT(GSHMe)2 to Detect Gamma Glutamyl Transferase Over Expressing Tumors

Harleen Khurana; Virendra Kumar Meena; Surbhi Prakash; Krishna Chuttani; Nidhi Chadha; Ambika Jaswal; Devinder Kumar Dhawan; Anil Kumar Mishra; Puja Panwar Hazari

doi:10.1371/journal.pone.0134281

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Open Access

Peer-reviewed

Research Article

Preclinical Evaluation of a Potential GSH Ester Based PET/SPECT Imaging Probe DT(GSHMe)₂ to Detect Gamma Glutamyl Transferase Over Expressing Tumors

Harleen Khurana,

Affiliations Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India, Department of Biophysics, Biomedical Sciences Block, Panjab University, Chandigarh, India
⨯
Virendra Kumar Meena,

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Surbhi Prakash,

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Krishna Chuttani,

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Nidhi Chadha,

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Ambika Jaswal,

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Devinder Kumar Dhawan,

Affiliation Department of Biophysics, Biomedical Sciences Block, Panjab University, Chandigarh, India
⨯
Anil Kumar Mishra ,

* E-mail: puja.hazari@gmail.com (PPH); akmishra63@gmail.com (AKM)

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯
Puja Panwar Hazari

* E-mail: puja.hazari@gmail.com (PPH); akmishra63@gmail.com (AKM)

Affiliation Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
⨯

Preclinical Evaluation of a Potential GSH Ester Based PET/SPECT Imaging Probe DT(GSHMe)₂ to Detect Gamma Glutamyl Transferase Over Expressing Tumors

Harleen Khurana,
Virendra Kumar Meena,
Surbhi Prakash,
Krishna Chuttani,
Nidhi Chadha,
Ambika Jaswal,
Devinder Kumar Dhawan,
Anil Kumar Mishra,
Puja Panwar Hazari

Published: July 29, 2015
https://doi.org/10.1371/journal.pone.0134281

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Glutathione
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