Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts

Patricia Coutinho de Souza; Samantha Mallory; Nataliya Smith; Debra Saunders; Xiao-Nan Li; Rene Y. McNall-Knapp; Kar-Ming Fung; Rheal A. Towner

doi:10.1371/journal.pone.0134276

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Peer-reviewed

Research Article

Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts

Patricia Coutinho de Souza,

Affiliations Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States of America, Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, United States of America
⨯
Samantha Mallory,

Affiliation University of Oklahoma Children's Hospital, Oklahoma City, OK, United States of America
⨯
Nataliya Smith,

Affiliation Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States of America
⨯
Debra Saunders,

Affiliation Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States of America
⨯
Xiao-Nan Li,

Affiliation Laboratory of Molecular Neuro-Oncology, Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX, United States of America
⨯
Rene Y. McNall-Knapp,

Affiliation University of Oklahoma Children's Hospital, Oklahoma City, OK, United States of America
⨯
Kar-Ming Fung,

Affiliations Peggy and Charles Stephenson Cancer Center, Oklahoma City, OK, United States of America, Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States of America, Department of Pathology, Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, United States of America
⨯
Rheal A. Towner

* E-mail: Rheal-Towner@omrf.org

Affiliations Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States of America, Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, United States of America, Peggy and Charles Stephenson Cancer Center, Oklahoma City, OK, United States of America
⨯

Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts

Patricia Coutinho de Souza,
Samantha Mallory,
Nataliya Smith,
Debra Saunders,
Xiao-Nan Li,
Rene Y. McNall-Knapp,
Kar-Ming Fung,
Rheal A. Towner

Published: August 6, 2015
https://doi.org/10.1371/journal.pone.0134276

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