Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling

Xin-Pei Wang; Fan Lei; Feng Du; Yu-Shuang Chai; Jing-Fei Jiang; Yu-Gang Wang; Xuan Yu; Xiao-Jin Yan; Dong-Ming Xing; Li-Jun Du

doi:10.1371/journal.pone.0134044

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Open Access

Peer-reviewed

Research Article

Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling

Xin-Pei Wang ,

Contributed equally to this work with: Xin-Pei Wang, Fan Lei

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Fan Lei ,

Contributed equally to this work with: Xin-Pei Wang, Fan Lei

Affiliation School of Medicine, Tsinghua University, Beijing, 100084, China
⨯
Feng Du,

Affiliation Department of Mathematics, Tulane University, New Orleans, LA, 70118, United States of America
⨯
Yu-Shuang Chai,

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Jing-Fei Jiang,

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Yu-Gang Wang,

Affiliation MD Anderson Cancer Center, University of Texas, Houston, Texas, 77030, United States of America
⨯
Xuan Yu,

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Xiao-Jin Yan,

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Dong-Ming Xing,

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯
Li-Jun Du

* E-mail: lijundu@mail.tsinghua.edu.cn

Affiliation MOE Key Laboratory of Protein Sciences, Laboratory of Molecular Pharmacology and Pharmaceutical Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China
⨯

Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling

Xin-Pei Wang,
Fan Lei,
Feng Du,
Yu-Shuang Chai,
Jing-Fei Jiang,
Yu-Gang Wang,
Xuan Yu,
Xiao-Jin Yan,
Dong-Ming Xing,
Li-Jun Du

Published: July 30, 2015
https://doi.org/10.1371/journal.pone.0134044

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