A Novel Mutation of DAX-1 Associated with Secretory Azoospermia

Lisha Mou; Nie Xie; Lihua Yang; Yuchen Liu; Ruiying Diao; Zhiming Cai; Honggang Li; Yaoting Gui

doi:10.1371/journal.pone.0133997

Loading metrics

Open Access

Peer-reviewed

Research Article

A Novel Mutation of DAX-1 Associated with Secretory Azoospermia

Lisha Mou ,

Contributed equally to this work with: Lisha Mou, Nie Xie

Affiliations Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Domesticated Organ Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China, Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, 518036, China
⨯
Nie Xie ,

Contributed equally to this work with: Lisha Mou, Nie Xie

Affiliations Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Domesticated Organ Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China, Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, 518036, China
⨯
Lihua Yang,

Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, 518036, China
⨯
Yuchen Liu,

Affiliation Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Domesticated Organ Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China
⨯
Ruiying Diao,

Affiliation Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Domesticated Organ Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China
⨯
Zhiming Cai,

Affiliation Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Domesticated Organ Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China
⨯
Honggang Li ,

* E-mail: guiyaoting2007@aliyun.com (YG); lhgyx@hotmail.com (HL)

Affiliation The Center of Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
⨯
Yaoting Gui

* E-mail: guiyaoting2007@aliyun.com (YG); lhgyx@hotmail.com (HL)

Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, 518036, China
⨯

A Novel Mutation of DAX-1 Associated with Secretory Azoospermia

Lisha Mou,
Nie Xie,
Lihua Yang,
Yuchen Liu,
Ruiying Diao,
Zhiming Cai,
Honggang Li,
Yaoting Gui

Published: July 24, 2015
https://doi.org/10.1371/journal.pone.0133997

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Missense mutation
Is the Subject Area "Missense mutation" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Spermatogenesis
Is the Subject Area "Spermatogenesis" applicable to this article?

Thanks for your feedback.
Luciferase
Is the Subject Area "Luciferase" applicable to this article?

Thanks for your feedback.
HeLa cells
Is the Subject Area "HeLa cells" applicable to this article?

Thanks for your feedback.
Mutation detection
Is the Subject Area "Mutation detection" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.