Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients

Mary Carmen Valenzano; Katherine DiGuilio; Joanna Mercado; Mimi Teter; Julie To; Brendan Ferraro; Brittany Mixson; Isabel Manley; Valerissa Baker; Beverley A. Moore; Joshua Wertheimer; James M. Mullin

doi:10.1371/journal.pone.0133926

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Peer-reviewed

Research Article

Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients

Mary Carmen Valenzano,

Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, 19096, United States of America
⨯
Katherine DiGuilio,

Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, 19096, United States of America
⨯
Joanna Mercado,

Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, 19096, United States of America
⨯
Mimi Teter,

Affiliation Department of Biology, Drexel University, Philadelphia, PA, 19104, United States of America
⨯
Julie To,

Affiliation Department of Biology, Drexel University, Philadelphia, PA, 19104, United States of America
⨯
Brendan Ferraro,

Affiliation Department of Biology, Drexel University, Philadelphia, PA, 19104, United States of America
⨯
Brittany Mixson,

Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, 19096, United States of America
⨯
Isabel Manley,

Affiliation Department of Biology, Drexel University, Philadelphia, PA, 19104, United States of America
⨯
Valerissa Baker,

Affiliation Department of Biology, Drexel University, Philadelphia, PA, 19104, United States of America
⨯
Beverley A. Moore,

Affiliation Janssen Research & Development, LLC, Spring House, PA, 19477, United States of America
⨯
Joshua Wertheimer,

Affiliation Janssen Research & Development, LLC, Spring House, PA, 19477, United States of America
⨯
James M. Mullin

* E-mail: mullinj@mlhs.org

Affiliations Lankenau Institute for Medical Research, Wynnewood, PA, 19096, United States of America, Division of Gastroenterology, Lankenau Medical Center, Wynnewood, PA, 19096, United States of America
⨯

Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients

Mary Carmen Valenzano,
Katherine DiGuilio,
Joanna Mercado,
Mimi Teter,
Julie To,
Brendan Ferraro,
Brittany Mixson,
Isabel Manley,
Valerissa Baker,
Beverley A. Moore

Published: July 30, 2015
https://doi.org/10.1371/journal.pone.0133926

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Indoles
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Cell differentiation
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Tight junctions
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