Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population

YongPing Chen; Qian-Qian Wei; RuWei Ou; Bei Cao; XuePing Chen; Bi Zhao; XiaoYan Guo; Yuan Yang; Ke Chen; Ying Wu; Wei Song; Hui-Fang Shang

doi:10.1371/journal.pone.0133776

Loading metrics

Open Access

Peer-reviewed

Research Article

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population

YongPing Chen ,

Contributed equally to this work with: YongPing Chen, Qian-Qian Wei

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Qian-Qian Wei ,

Contributed equally to this work with: YongPing Chen, Qian-Qian Wei

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
RuWei Ou,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Bei Cao,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
XuePing Chen,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Bi Zhao,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
XiaoYan Guo,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Yuan Yang,

Affiliation Department of Medical Genetics, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Ke Chen,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Ying Wu,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Wei Song,

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯
Hui-Fang Shang

* E-mail: hfshang2002@163.com

Affiliation Department of Neurology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
⨯

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population

YongPing Chen,
Qian-Qian Wei,
RuWei Ou,
Bei Cao,
XuePing Chen,
Bi Zhao,
XiaoYan Guo,
Yuan Yang,
Ke Chen,
Ying Wu

Published: July 24, 2015
https://doi.org/10.1371/journal.pone.0133776

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Parkinson disease
Is the Subject Area "Parkinson disease" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Haplotypes
Is the Subject Area "Haplotypes" applicable to this article?

Thanks for your feedback.
Amyotrophic lateral sclerosis
Is the Subject Area "Amyotrophic lateral sclerosis" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.
Alleles
Is the Subject Area "Alleles" applicable to this article?

Thanks for your feedback.
Chinese people
Is the Subject Area "Chinese people" applicable to this article?

Thanks for your feedback.