The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo

Xuewen Jin; Yuling Liu; Jingjing Liu; Weiliang Lu; Ziwei Liang; Dan Zhang; Gang Liu; Hongxia Zhu; Ningzhi Xu; Shufang Liang

doi:10.1371/journal.pone.0133770

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Open Access

Peer-reviewed

Research Article

The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo

Xuewen Jin,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Yuling Liu,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Jingjing Liu,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Weiliang Lu,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Ziwei Liang,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Dan Zhang,

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯
Gang Liu,

Affiliation Department of Rheumatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, P. R. China
⨯
Hongxia Zhu,

Affiliation Laboratory of Cell and Molecular Biology & State Key Laboratory of Molecular Oncology, Cancer Institute & Cancer Hospital, Chinese Academy of Medical Sciences, Beijing,100034, P. R. China
⨯
Ningzhi Xu,

Affiliation Laboratory of Cell and Molecular Biology & State Key Laboratory of Molecular Oncology, Cancer Institute & Cancer Hospital, Chinese Academy of Medical Sciences, Beijing,100034, P. R. China
⨯
Shufang Liang

* E-mail: zizi2006@scu.edu.cn

Affiliation State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, No.17, 3rd Section of People's South Road, Chengdu, 610041, P. R. China
⨯

The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo

Xuewen Jin,
Yuling Liu,
Jingjing Liu,
Weiliang Lu,
Ziwei Liang,
Dan Zhang,
Gang Liu,
Hongxia Zhu,
Ningzhi Xu,
Shufang Liang

Published: August 7, 2015
https://doi.org/10.1371/journal.pone.0133770

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