The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy

• Yutaka Ohsawa ,

  * E-mail: yosawa@med.kawasaki-m.ac.jp (YO); ysunada@med.kawasaki-m.ac.jp (YS)

  Affiliation Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan

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• Kentaro Takayama,

  Affiliation Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, 192–0392, Japan

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• Shin-ichiro Nishimatsu,

  Affiliation Department of Molecular and Developmental Biology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan

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• Tadashi Okada,

  Affiliations Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan, National Research Center for Protozoan Diseases (NRCPD), Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080–8555, Japan

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• Masahiro Fujino,

  Affiliations Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan, Department of Health and Sports Sciences, Faculty of Medical Professions, Kawasaki University of Medical Welfare, Kurashiki, Okayama, 701–0193, Japan

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• Yuta Fukai,

  Affiliation Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan

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• Tatsufumi Murakami,

  Affiliation Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan

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• Hiroki Hagiwara,

  Affiliation Department of Medical Science, Teikyo University of Science, Uenohara, Yamanashi, 409–0193, Japan

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• Fumiko Itoh,

  Affiliation Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, 192–0392, Japan

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• Kunihiro Tsuchida,

  Affiliation Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470–1192, Japan

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• Yoshio Hayashi,

  Affiliation Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, 192–0392, Japan

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• Yoshihide Sunada

  * E-mail: yosawa@med.kawasaki-m.ac.jp (YO); ysunada@med.kawasaki-m.ac.jp (YS)

  Affiliation Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, 701–0192, Japan

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