Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages

Anouk A. J. Hamers; Laura van Dam; José M. Teixeira Duarte; Mariska Vos; Goran Marinković; Claudia M. van Tiel; Sybren L. Meijer; Anne-Marieke van Stalborch; Stephan Huveneers; Anje A. te Velde; Wouter J. de Jonge; Carlie J. M. de Vries

doi:10.1371/journal.pone.0133598

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Open Access

Peer-reviewed

Research Article

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages

Anouk A. J. Hamers,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Laura van Dam,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
José M. Teixeira Duarte,

Affiliation Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Mariska Vos,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Goran Marinković,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Claudia M. van Tiel,

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Sybren L. Meijer,

Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Anne-Marieke van Stalborch,

Affiliation Department of Molecular Cell Biology, Sanquin Research and Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
⨯
Stephan Huveneers,

Affiliation Department of Molecular Cell Biology, Sanquin Research and Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
⨯
Anje A. te Velde,

Affiliation Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Wouter J. de Jonge ,

Contributed equally to this work with: Wouter J. de Jonge, Carlie J. M. de Vries

Affiliation Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Carlie J. M. de Vries

Contributed equally to this work with: Wouter J. de Jonge, Carlie J. M. de Vries

* E-mail: c.j.devries@amc.uva.nl

Affiliation Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages

Anouk A. J. Hamers,
Laura van Dam,
José M. Teixeira Duarte,
Mariska Vos,
Goran Marinković,
Claudia M. van Tiel,
Sybren L. Meijer,
Anne-Marieke van Stalborch,
Stephan Huveneers,
Anje A. te Velde

Published: August 4, 2015
https://doi.org/10.1371/journal.pone.0133598

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