Establishment of a High-Throughput Assay to Monitor Influenza A Virus RNA Transcription and Replication

Zhen Wang; Fei Zhao; Qian Gao; Zhenlong Liu; Yongxin Zhang; Xiaoyu Li; Yuhuan Li; Weilie Ma; Tao Deng; Zhizhen Zhang; Shan Cen

doi:10.1371/journal.pone.0133558

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Open Access

Peer-reviewed

Research Article

Establishment of a High-Throughput Assay to Monitor Influenza A Virus RNA Transcription and Replication

Zhen Wang,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Fei Zhao,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Qian Gao,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Zhenlong Liu,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Yongxin Zhang,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Xiaoyu Li,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Yuhuan Li,

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Weilie Ma,

Affiliation Department of Biochemistry, Guangdong Medical College, Zhanjiang, Guangdong, China
⨯
Tao Deng,

Affiliation Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯
Zhizhen Zhang ,

* E-mail: shancen@imb.pumc.edu.cn (SC); zzzhang@gdmc.edu.cn (ZZ)

Affiliation Department of Biochemistry, Guangdong Medical College, Zhanjiang, Guangdong, China
⨯
Shan Cen

* E-mail: shancen@imb.pumc.edu.cn (SC); zzzhang@gdmc.edu.cn (ZZ)

Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Pekin Union Medical College, Beijing, China
⨯

Establishment of a High-Throughput Assay to Monitor Influenza A Virus RNA Transcription and Replication

Zhen Wang,
Fei Zhao,
Qian Gao,
Zhenlong Liu,
Yongxin Zhang,
Xiaoyu Li,
Yuhuan Li,
Weilie Ma,
Tao Deng,
Zhizhen Zhang

Published: July 21, 2015
https://doi.org/10.1371/journal.pone.0133558

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