Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

Gillian O'Hurley; Christer Busch; Linn Fagerberg; Björn M. Hallström; Charlotte Stadler; Anna Tolf; Emma Lundberg; Jochen M. Schwenk; Karin Jirström; Anders Bjartell; William M. Gallagher; Mathias Uhlén; Fredrik Pontén

doi:10.1371/journal.pone.0133449

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Peer-reviewed

Research Article

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

Gillian O'Hurley,

Affiliations Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland, OncoMark Ltd, NovaUCD, Belfield Innovation Park, Belfield, Dublin 4, Ireland
⨯
Christer Busch,

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Linn Fagerberg,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Björn M. Hallström,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Charlotte Stadler,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Anna Tolf,

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Emma Lundberg,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Jochen M. Schwenk,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Karin Jirström,

Affiliation Department of Clinical Sciences Lund, Oncology and Pathology, Lund University, Skåne University Hospital, Lund, Sweden
⨯
Anders Bjartell,

Affiliation Department of Clinical Sciences, Division of Urological Cancers, Skåne University Hospital Malmö, Lund University, Malmö, Sweden
⨯
William M. Gallagher,

Affiliation UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
⨯
Mathias Uhlén,

Affiliation Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden
⨯
Fredrik Pontén

* E-mail: fredrik.ponten@igp.uu.se

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

Gillian O'Hurley,
Christer Busch,
Linn Fagerberg,
Björn M. Hallström,
Charlotte Stadler,
Anna Tolf,
Emma Lundberg,
Jochen M. Schwenk,
Karin Jirström,
Anders Bjartell

Published: August 3, 2015
https://doi.org/10.1371/journal.pone.0133449

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Prostate gland
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Protein expression
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Small interfering RNA
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