A Proline-Rich Domain in the Genotype 4 Hepatitis E Virus ORF3 C-Terminus Is Crucial for Downstream V105DLP108 Immunoactivity

Heng Wang; Fangxiao Ji; Huanbin Liang; Honglang Gu; Zhangyong Ning; Rongchang Liu; Guihong Zhang

doi:10.1371/journal.pone.0133282

Loading metrics

Open Access

Peer-reviewed

Research Article

A Proline-Rich Domain in the Genotype 4 Hepatitis E Virus ORF3 C-Terminus Is Crucial for Downstream V¹⁰⁵DLP¹⁰⁸ Immunoactivity

Heng Wang ,

Contributed equally to this work with: Heng Wang, Fangxiao Ji, Huanbin Liang

Affiliations College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, China, Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, 510642, China
⨯
Fangxiao Ji ,

Contributed equally to this work with: Heng Wang, Fangxiao Ji, Huanbin Liang

Affiliations College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, China, MOA Key Laboratory of Animal Vaccine Development, Guangzhou, Guangdong Province, 510642, China
⨯
Huanbin Liang ,

Contributed equally to this work with: Heng Wang, Fangxiao Ji, Huanbin Liang

Affiliation MOA Key Laboratory of Animal Vaccine Development, Guangzhou, Guangdong Province, 510642, China
⨯
Honglang Gu,

Affiliation MOA Key Laboratory of Animal Vaccine Development, Guangzhou, Guangdong Province, 510642, China
⨯
Zhangyong Ning,

Affiliations College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, China, Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, 510642, China
⨯
Rongchang Liu,

Affiliation Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, 510642, China
⨯
Guihong Zhang

* E-mail: guihongzh@scau.edu.cn

Affiliations College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, China, MOA Key Laboratory of Animal Vaccine Development, Guangzhou, Guangdong Province, 510642, China
⨯

A Proline-Rich Domain in the Genotype 4 Hepatitis E Virus ORF3 C-Terminus Is Crucial for Downstream V¹⁰⁵DLP¹⁰⁸ Immunoactivity

Heng Wang,
Fangxiao Ji,
Huanbin Liang,
Honglang Gu,
Zhangyong Ning,
Rongchang Liu,
Guihong Zhang

Published: July 15, 2015
https://doi.org/10.1371/journal.pone.0133282

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
Phage display
Is the Subject Area "Phage display" applicable to this article?

Thanks for your feedback.
Bacteriophages
Is the Subject Area "Bacteriophages" applicable to this article?

Thanks for your feedback.
Hepatitis E virus
Is the Subject Area "Hepatitis E virus" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Recombinant proteins
Is the Subject Area "Recombinant proteins" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Protein sequencing
Is the Subject Area "Protein sequencing" applicable to this article?

Thanks for your feedback.