Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

• James E. Korkola,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Eric A. Collisson,

  Affiliation University of California San Francisco, Division of Heme/Onc, San Francisco, California, United States of America

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• Laura Heiser,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Chris Oates,

  Affiliations Netherlands Cancer Institute, Division of Biochemistry, Amsterdam, The Netherlands, University of Warwick, Centre for Complexity Science, Coventry, United Kingdom

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• Nora Bayani,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Sleiman Itani,

  Affiliation University of California, Berkeley, Department of Electrical Engineering and Computer Sciences, Berkeley, California, United States of America

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• Amanda Esch,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Wallace Thompson,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Obi L. Griffith,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Nicholas J. Wang,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Wen-Lin Kuo,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Brian Cooper,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Jessica Billig,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Safiyyah Ziyad,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Jenny L. Hung,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Lakshmi Jakkula,

  Affiliation Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Heidi Feiler,

  Affiliations Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America, Lawrence Berkeley National Laboratories, Life Sciences Division, Berkeley, California, United States of America

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• Yiling Lu,

  Affiliation MD Anderson Cancer Center, Department of Systems Biology, Houston, Texas, United States of America

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• Gordon B. Mills,

  Affiliation MD Anderson Cancer Center, Department of Systems Biology, Houston, Texas, United States of America

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• Paul T. Spellman,

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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• Claire Tomlin,

  Affiliation University of California, Berkeley, Department of Electrical Engineering and Computer Sciences, Berkeley, California, United States of America

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• Sach Mukherjee,

  Current address: German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

  Affiliation Netherlands Cancer Institute, Division of Biochemistry, Amsterdam, The Netherlands

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•  [ ... ],
• Joe W. Gray

  * E-mail: grayjo@ohsu.edu

  Affiliation Oregon Health Sciences University, Department of Biomedical Engineering, Portland, Oregon, United States of America

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